Publication:
Relationship between p16 and tumor-infiltrating lymphocytes in Peruvian patients with head and neck cancer
Relationship between p16 and tumor-infiltrating lymphocytes in Peruvian patients with head and neck cancer
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Date
2021
Authors
Castaneda, C. A.
Castillo Garcia, M.
Bernabe, L. A.
Sanchez, J.
Tello, K.
Alatrsita, R.
Villa, L.
Sichero, L.
Enciso, J.
Guerra, H.
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Volume Title
Publisher
Elsevier
Research Projects
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Abstract
Human papillomavirus-16 (HPV-16) infection in Head and Neck Squamous Cell Carcinoma (HNSCC) has a different prevalence through worldwide regions, it influences prognosis and treatment response and p16 staining is its surrogate biomarker. The density and composition of tumor-infiltrating lymphocytes (TIL) reflect biology and prognosis in different malignancies. We characterize TIL in Peruvian patients with HNSCC. We evaluate the influence of clinicopathological features including p16 & ki67 staining in tumor cells over TIL level.
Description
FONDECYT 096-2017.
Keywords
peruvian patients,
cancer