Publication:
Cleavage and development in cultured preimplantation mouse embryos exposed to lidocaine
Cleavage and development in cultured preimplantation mouse embryos exposed to lidocaine
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Date
1996
Authors
Del Valle L.J.
Orihuela P.A.
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Publisher
Elsevier
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Abstract
Two-cell preimplantation mouse embryos were exposed in vitro to lidocaine (0 to 1,000 μg/mL) for 72 h to determine the effects of this anesthetic on subsequent cleavage and development during prolonged exposures. Embryonic development was monitored each 24 h for 3 d. Lidocaine adversely affected the in vitro development of the mouse embryos, altering the distribution of the development stages at the evaluated culture tunes.
Description
Acknowledgments -This investigationw as supportedb y a grant from the Sciences and Technology National Council (CONCYTEC, Project No 2043) Lima-Peru.
Keywords
Genética animal,
Embrión