Publication:
Pyrrolizidine Alkaloids of Senecio sp from Peru
Pyrrolizidine Alkaloids of Senecio sp from Peru
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Date
2011
Authors
Vasquez, LR
Artiles, MR
Coloma, AG
Perez, RC
Mesia, LR
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Sociedade Brasileira de Quimica
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Abstract
Six pyrrolizidine alkaloids (PAs) (two saturated macrocyclic, three unsaturated macrocyclic and one unsaturated seco-macrocyclic) were isolated from native Peruvian Senecio species. The structures of these alkaloids were established by a complete NMR spectroscopic analysis, chemical transformations and comparison of their NMR data with those published for similar alkaloids. Three PAs were then tested for antifungal activity against Fusarium moniliforme, F. (Sheldon), F. oxysporum fs. lycopersici (Scheldt) and F. solani (Mart), no significant activity being observed.
Description
This work was supported by a Collaborative Research Grant from CSIC-CONCYTEC, National University of the Peruvian Amazonia, Iquitos, Peru, Ministerio de Educacion y Ciencia, Spain (CTQ2009-14629-C02-01) and a predoctoral MAEC-AECID fellowship to L. R. Vasquez.
Keywords
Senecio,
19-acetoxisenkirkina,
alcaloides de pirrolizidina